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10x Flex preserves biological processes
The 10x Genomics Flex kit for single-cell RNA-sequencing relies on a fixed set of gene probes as opposed to untargeted RNA-sequencing.
May 10 • Valentine Svensson

Recent posts

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Creating a Tahoe sculpture
Last year, the company I work for rebranded as Tahoe Therapeutics. It is named after Lake Tahoe at the border between California and Nevada.
May 4 • Valentine Svensson
Improving SCVI for low-count cells through self-supervised augmentation
To improve utility of cells with low UMI counts, I wanted to optimize KL weighting in SCVI models.
Mar 2 • Valentine Svensson
Serverless GPUs for fast TSNE visualization
TSNE visualization is useful to explore data but is time consuming without access to an Nvidia GPU.
Jan 21 • Valentine Svensson
Training SCVI - Metal acceleration
The single cell analysis package scvi-tools allow you to model data quickly and easily if you have access to a GPU.
Jan 15 • Valentine Svensson
SCVI - Estimating null expression levels
In this post I motivate why I think it would be useful to have clear thresholds for when a gene is not expressed, test a strategy to obtain such…
Jan 6 • Valentine Svensson
Claude agent skill to infer experimental designs from .h5ad’s
Anthropic recently launched Claude for Life Sciences, which in practical terms means a marketplace of plugins, MCP’s, and agent skills focused on tasks…
Nov 14, 2025 • Valentine Svensson
Training SCVI — Differential expression over epochs
With a trained SCVI model you can perform differential expression analysis to learn which genes are increased and decreased in gene expression as cells…
Oct 14, 2025 • Valentine Svensson
Top posts
SCVI — Integrating or not?
Mar 18, 2025 • Valentine Svensson
Actionable scRNA-seq clusters
Mar 5, 2018 • Valentine Svensson
Slot machine strategy
Jul 6, 2025 • Valentine Svensson
Merging SCVI models
May 21, 2025 • Valentine Svensson
SCVI with variational batch encoding
Jun 21, 2025 • Valentine Svensson
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