Power Analysis of Single Cell RNA-Sequencing Experiments

Valentine Svensson, Kedar Nath Natarajan, Lam-Ha Ly, Ricardo Miragaia, Charlotte Labalette, Iain M. Macaulay, Ana Cvejic & Sarah A. Teichmann,

Nature Methods (2017) | doi:10.1038/nmeth.4220

Public Fulltext | In Journal | umis Software

 
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Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria

Tapio Lönnberg, Valentine Svensson, Kylie R. James, Daniel Fernandez-Ruiz, Ismail Sebina, Ruddy Montandon, Megan S. F. Soon, Lily G. Fogg, Arya Sheela Nair, Urijah N. Liligeto, Michael J. T. Stubbington, Lam-Ha Ly, Frederik Otzen Bagger, Max Zwiessele, Neil D. Lawrence, Fernando Souza-Fonseca-Guimaraes, Patrick T. Bunn, Christian R. Engwerda, William R. Heath, Oliver Billker,Oliver Stegle, Ashraful Haque, Sarah A. Teichmann

Science Immunology (2017)

Link to Public Fulltext

 

Single-cell analysis at the threshold

Xi Chen, J Christopher Love, Nicholas E Navin, Lior Pachter, Michael J T Stubbington, Valentine Svensson, Jonathan V Sweedler & Sarah A Teichmann

Nature Biotechnology (2016)

 
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MERVL/Zscan4 Network Activation Results in Transient Genome-wide DNA Demethylation of mESCs

Mélanie A. Eckersley-Maslin, Valentine Svensson, Christel Krueger, Thomas M. Stubbs, Pascal Giehr, Felix Krueger, Ricardo J. Miragaia, Charalampos Kyriakopoulos, Rebecca V. Berrens, Inês Milagre, Jörn Walter, Sarah A. Teichmann, Wolf Reik

Cell Reports (2016)

 
 

Single-cell analysis of CD4+ T-cell differentiation reveals three major cell states and progressive acceleration of proliferation

Valentina Proserpio, Andrea Piccolo, Liora Haim-Vilmovsky, Gozde Kar, Tapio Lönnberg, Valentine Svensson, Jhuma Pramanik, Kedar Nath Natarajan, Weichao Zhai, Xiuwei Zhang, Giacomo Donati, Melis Kayikci, Jurij Kotar, Andrew NJ McKenzie, Ruddy Montandon, Oliver Billker, Steven Woodhouse, Pietro Cicuta, Mario Nicodemi, Sarah A Teichmann,

Genome Biology (2016)

 

Single cell RNA-sequencing reveals a continuous spectrum of differentiation in haematopoietic cells

Iain C. Macaulay, Valentine Svensson, Charlotte Labalette, Lauren Ferreira, Fiona Hamey, Thierry Voet, Sarah A. Teichmann, Ana Cvejic

Cell Reports (2016)

Analysis Notebooks

 

The Technology and Biology of Single-Cell RNA Sequencing

Aleksandra A Kolodziejczyk, Jong Kyoung Kim, Valentine Svensson, John C. Marioni, Sarah A. Teichmann,

Molecular Cell (2015)

 
 

An atlas of mouse CD4+ T cell transcriptomes

Michael J. T. Stubbington, Bidesh Mahata, Valentine Svensson, Andrew Deonarine, Jesper K. Nissen, Alexander G. Betz, Sarah A. Teichmann

Biology direct (2015)